We give you the hints to kickstart your improvement journey.

The hot spot analysis explores the enzyme’s evolutionary history, assesses its structural characteristics, and examines its interactions with substrates. We also conduct an in-depth literature review to leverage existing insights and knowledge.

Our analysis includes:

•Statistical modelling

•Force field-based methods

•Rational design

This foundational step is essential for narrowing down the sequence space, making experimental testing more time and cost-efficient. Additionally, it highlights key regions within the protein with the potential for enhanced activity and stability through targeted modifications.